By Larry B. Goldstein
Society-sanctioned instructions are helpful instruments, yet getting access to key info could be a daunting activity. This ebook illuminates a transparent route to winning program of the yank center Association/American Stroke organization guidance. equipped for quick reference, this new quantity is helping practitioners enhance sufferer care.
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Additional info for A Primer on Stroke Prevention and Treatment: An overview based on AHA/ASA Guidelines
Tight control of hypertension with BP target <130/80; use of ACE-I or ARB; use of statin. 0) is recommended for high (>4% annual stroke risk) and moderate risk patients with nonvalvular AFib. Warfarin for patients with MI and ST-elevation syndrome, as well as for patients with MI and LV dysfunction. Patients with known heart disease or high-risk hypertensive patients should be treated with lifestyle measures and a statin or with niacin versus gemfibrozil if they have low HDL. Therapy of all identified stroke risk factors, use of aspirin.
ACE-I, angiotensin-converting enzyme inhibitor; AFib, atrial fibrillation; ARB, angiotensin receptor blocker; BP, blood pressure; CDC, Centers for Disease Control; HDL, high-density lipoprotein; hs-CRP, high-sensitivity C-reactive protein; JNC 7, Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure; LV, left ventricle; MI, myocardial infarction; NIH, National Institutes of Health; SCD, sickle-cell disease; TCD, transcranial Doppler. studies have shown a strong correlation between CRP levels and cardiovascular/cerebrovascular events with a 2- to 3-fold increase in stroke risk.
The data on the relationship between low-density lipoprotein (LDL) cholesterol and ischemic stroke are weaker, whereas several studies have shown increased prevalence of ischemic stroke in persons with low high-density lipoprotein Chapter 3 Primordial and Primary Prevention of Stroke (HDL) cholesterol (especially less than 30 mg/dL) . Elevated triglycerides are also associated with higher rates of cerebral ischemia. , HPS, Anglo-Scandinavian Cardiac Outcomes Trial) [30,31]. A recent trial evaluated the use of an inhibitor of cholesteryl esterase transfer protein, torcetrapib, which has been shown to increase HDL cholesterol, in reducing major cardiovascular events.
A Primer on Stroke Prevention and Treatment: An overview based on AHA/ASA Guidelines by Larry B. Goldstein